Paroxysmal nocturnal hemoglobinuria in myelofibrosis.

Ten consecutive patients with myeloysis. One patient had a positive sucrose fibrosis were examined for the following hemolysis test and low red cell ACHE. signs of PNH: Ham’s test, the sucrose The remaining patients had no signs of hemolysis test, low red cell acetylcholinPNH. In two of the patients, the PNH esterase (ACHE) activity and intrasigns disappeared after splenectomy. The vascular hemolysis. Two of the patients concurrence of myelofibrosis and PNH displayed all these signs and also had supports the hypothesis that PNH is a clinical symptoms of PNH. Two patients disease of the common hemopoietic stem had positive sucrose hemolysis tests, low cell. red cell ACHE and intravascular hemol-